Daivonex 30 gm

What is Daivonex Ointment

Daivonex 30 gm is a prescription topical ointment used to treat mild to moderate Plaque Psoriasis, a skin condition that causes raised, red, scaly patches. It contains FDA-approved Calcipotriol 50 mcg, a synthetic analog of Vitamin D3. The ointment is manufactured by Win Medicare, India, in GMP-compliant facilities.

Calcipotriol works by binding to Vitamin D receptors on skin cells called keratinocytes, slowing their abnormal overproduction and promoting normal cell differentiation. It also lowers the activity of certain immune cells in the skin that drive the inflammatory component of Psoriasis. Over time, this normalizes the skin’s appearance by reducing scaling, thickening, and redness at the plaque sites.

Apply Daivonex Ointment to the affected areas once or twice daily, or as directed by a doctor. Gently rub it into the plaques until fully absorbed. Wash hands thoroughly after each application unless the hands are the area being treated. Avoid touching the face, eyes, and mucous membranes after using the ointment.

Common side effects of Calcipotriol include mild skin irritation and burning at the application site, particularly during the first few weeks of use. These typically subside as treatment continues.

Store Daivonex Ointment at room temperature below 25°C. Keep it away from direct sunlight and moisture. Ensure the tube is tightly closed and out of reach of children. Do not use it after the expiry date.

What are the benefits of using Daivonex Ointment

Calcipotriol targets the root cause of Plaque Psoriasis by correcting the abnormal skin cell cycle and reducing the localized immune activity that sustains the plaques. Unlike corticosteroid-based treatments, Calcipotriol does not cause skin thinning with long-term use, making it suitable for extended treatment of persistent plaques. It helps reduce inflammation and flattens thickened, raised skin.

How to use Daivonex Ointment

Daivonex Ointment is a prescription topical medication that should be used only as directed by a healthcare professional. General application guidelines are as follows:

• Apply a thin layer to the affected plaques once or twice daily, gently massaging it into the skin until fully absorbed.
• Wash hands thoroughly before and after application unless the hands are the area being treated.
• Avoid applying near the eyes, mouth, or mucous membranes. Rinse with water immediately if accidental contact occurs. Do not apply to the face or skin folds unless specifically directed by a doctor.
• Do not exceed the weekly dose limit of 100 g for adults, or as recommended by your doctor.

Strengths and Substitutes

Currently, Daivonex is only available as a 50 mcg/g Calcipotriol ointment. However, you can consider these alternatives at Cheap Medicine Shop.

View all substitutes

What are the side effects of Daivonex Ointment

While generally safe, Daivonex Ointment can cause mild side effects, usually localized to the application site. However, consult a qualified healthcare professional if they persist or worsen:

• Burning or stinging
• Itching
• Skin dryness or peeling
• Redness or mild rash around the treated area
• Worsening of Psoriasis
• Skin irritation or Dermatitis on the surrounding healthy skin

Safety Advice

Liver Disease

Daivonex Ointment is applied topically and has minimal systemic absorption when used as directed. Patients with liver disease can generally use it safely without dose adjustments related to liver function. However, inform the doctor about any liver condition before starting treatment, particularly if other Vitamin D-related medications are being used simultaneously.

Kidney Impairment

Patients with kidney impairment should use Daivonex Ointment with caution and under close medical supervision. While systemic absorption is low under normal use, impaired kidneys are less able to manage changes in calcium and phosphate levels. Use over large body surface areas should be avoided in patients with kidney disease, and medical consultation is vital before treatment.

Pregnant and Breastfeeding women

Daivonex Ointment should be used during pregnancy only when clearly necessary and under medical supervision. Animal studies with high systemic doses of Calcipotriol have shown some fetal effects, though topical application results in minimal systemic absorption. Breastfeeding women should avoid applying the ointment to the chest or breast area. Consult a doctor before using during pregnancy or while nursing.

Avoid

Do not apply Daivonex to the face, eyes, or mucous membranes, as Calcipotriol can cause significant irritation in these areas. Do not use on infected, broken, or severely inflamed skin. Avoid using alongside other Vitamin D supplements or calcium supplements without medical guidance, as combined use can elevate blood calcium to unsafe levels. Patients with known disorders of calcium metabolism should not use this ointment.